2. Gene
  3. Rtn2 - reticulon 2 (Z-band associated protein) Gene

Rtn2 - reticulon 2 (Z-band associated protein) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ms10p; NSPLI; Nspl1; MMS10-P

Gene ID: 20167 | Gene type: protein coding

About Rtn2

Summary

Acts upstream of or within gene expression; intracellular protein transmembrane transport; and regulation of glucose import. Located in several cellular components, including T-tubule; Z disc; and terminal cisterna. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 12. Orthologous to human RTN2 (reticulon 2). [provided by Alliance of Genome Resources, Apr 2022]

Rtn2 Products(2)

mRNA Protein Name
NM_001025364.3 NP_001020535.1 reticulon-2 isoform C
NM_013648.6 NP_038676.1 reticulon-2 isoform B
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within gene expression IPI
IPI: Inferred from physical interaction
18096700 MGI
acts upstream of or within intracellular protein transmembrane transport IMP
IMP: Inferred from mutant phenotype
19720795 MGI
acts upstream of or within regulation of D-glucose import IMP
IMP: Inferred from mutant phenotype
19720795 MGI
Cellular Component GO Annotation Evidence Reference Source
located in T-tubule IDA
IDA: Inferred from direct assay
19720795 MGI
located in Z disc IDA
IDA: Inferred from direct assay
10672514 MGI
located in intermediate filament IDA
IDA: Inferred from direct assay
10672514 MGI
located in terminal cisterna IDA
IDA: Inferred from direct assay
19720795 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

reticulon-2

NSP-like protein 1

NSP-like protein I

neuroendocrine-specific protein-like 1

neuroendocrine-specific protein-like I

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12330 RTN2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22316 Rtn2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rtn2 NCBI NCBI:6253