2. Gene
  3. Ptpn18 - protein tyrosine phosphatase, non-receptor type 18 Gene

Ptpn18 - protein tyrosine phosphatase, non-receptor type 18 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FLP1; HSCF; Ptpk1; PTP-K1; PTP-HSCF

Gene ID: 19253 | Gene type: protein coding

About Ptpn18

Summary

Enables non-membrane spanning protein tyrosine Phosphatase activity. Acts upstream of or within blastocyst formation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Orthologous to human PTPN18 (protein tyrosine Phosphatase non-receptor type 18). [provided by Alliance of Genome Resources, Apr 2022]

Ptpn18 Products(1)

mRNA Protein Name
NM_011206.2 NP_035336.2 tyrosine-protein phosphatase non-receptor type 18
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables non-membrane spanning protein tyrosine phosphatase activity IDA
IDA: Inferred from direct assay
8875997 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9265651 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within blastocyst formation IMP
IMP: Inferred from mutant phenotype
27869233 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
8875997 MGI
located in nucleus IDA
IDA: Inferred from direct assay
8875997 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein phosphatase non-receptor type 18

FLP-1

fetal liver phosphatase 1

Ptpn18 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Ptpn18 Q61152 Pstpip1 Mus musculus P97814
Pull Down
9804817
Intra
Ptpn18 Q61152 Pstpip2 Mus musculus Q99M15
Anti Tag CoIP
9804817
Intra
Ptpn18 Q61152 Pstpip2 Mus musculus Q99M15
Competition Binding
9804817
Intra
Ptpn18 Q61152 Pstpip2 Mus musculus Q99M15
Pull Down
9804817
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11420 PTPN18 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20587 Ptpn18 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27095 Ptpn18 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptpn18 NCBI NCBI:26469