2. Gene
  3. Prg2 - proteoglycan 2, bone marrow Gene

Prg2 - proteoglycan 2, bone marrow Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MBP; EMBP; mMBP; mMBP-1

Gene ID: 19074 | Gene type: protein coding

About Prg2

Summary

Predicted to enable carbohydrate binding activity. Predicted to be an extracellular matrix structural constituent conferring compression resistance. Acts upstream of or within defense response to nematode; negative regulation of interleukin-10 production; and positive regulation of interleukin-4 production. Located in collagen-containing extracellular matrix. Is expressed in several structures, including immune system; liver; lung; and testis. Orthologous to human PRG2 (proteoglycan 2, pro eosinophil major basic protein). [provided by Alliance of Genome Resources, Apr 2022]

Prg2 Products(1)

mRNA Protein Name
NM_008920.4 NP_032946.1 bone marrow proteoglycan precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within defense response to nematode IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of interleukin-10 production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of macrophage cytokine production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of or within negative regulation of interleukin-10 production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of or within negative regulation of macrophage cytokine production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
acts upstream of or within positive regulation of interleukin-4 production IMP
IMP: Inferred from mutant phenotype
16926417 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bone marrow proteoglycan

BMPG

major basic protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11088 PRG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11479 PXDN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17666 Ptgr2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19939 Prg2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20464 Plpp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26441 Prg2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prg2 NCBI NCBI:5553