2. Gene
  3. Pold1 - polymerase (DNA directed), delta 1, catalytic subunit Gene

Pold1 - polymerase (DNA directed), delta 1, catalytic subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 125kDa

Gene ID: 18971 | Gene type: protein coding

About Pold1

Summary

Enables 3'-5' exonuclease activity and enzyme binding activity. Involved in DNA biosynthetic process. Acts upstream of or within DNA replication proofreading and base-excision repair, gap-filling. Part of delta DNA Polymerase complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human POLD1 (DNA Polymerase delta 1, catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]

Pold1 Products(1)

mRNA Protein Name
NM_011131.3 NP_035261.3 DNA polymerase delta catalytic subunit
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables 3'-5' exonuclease activity IMP
IMP: Inferred from mutant phenotype
12429860 MGI
enables enzyme binding IPI
IPI: Inferred from physical interaction
24115439 MGI
Biological Process GO Annotation Evidence Reference Source
involved in DNA biosynthetic process IDA
IDA: Inferred from direct assay
11595739 MGI
acts upstream of or within DNA replication proofreading IMP
IMP: Inferred from mutant phenotype
12429860 MGI
acts upstream of or within base-excision repair, gap-filling IMP
IMP: Inferred from mutant phenotype
15177179 MGI
Cellular Component GO Annotation Evidence Reference Source
part of delta DNA polymerase complex IDA
IDA: Inferred from direct assay
11595739 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA polymerase delta catalytic subunit

3'-5' exodeoxyribonuclease

DNA polymerase delta 1, catalytic domain

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10819 POLD1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18833 Pold1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25325 Pold1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pold1 NCBI NCBI:5424