2. Gene
  3. mt-Nd2 - NADH dehydrogenase 2, mitochondrial Gene

mt-Nd2 - NADH dehydrogenase 2, mitochondrial Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus (strain: C57BL/6J)

Also known as ND2

Gene ID: 17717 | Gene type: protein coding

About mt-Nd2

Summary

Predicted to enable NADH dehydrogenase (ubiquinone) activity; ionotropic glutamate receptor binding activity; and protein kinase binding activity. Acts upstream of or within Reactive Oxygen Species metabolic process. Located in mitochondrion. Is expressed in early conceptus and secondary oocyte. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder Cancer. Orthologous to human MT-ND2 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd2 Products(2)

mRNA Protein Name
NP_904329.1 NADH dehydrogenase subunit 2 (mitochondrion) [Mus musculus]
NP_904329.1 NADH dehydrogenase subunit 2 (mitochondrion) [Mus musculus]
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within reactive oxygen species metabolic process IDA
IDA: Inferred from direct assay
17189252 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase subunit 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08797 MT-ND2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20570 mt-Nd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27078 mt-Nd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Nd2 NCBI NCBI:4536