Mcm5 - minichromosome maintenance complex component 5 Gene

Mus musculus

Also known as Cdc46; Mcmd5; P1-CDC46

Gene ID: 17218 | Gene type: protein coding

About Mcm5

Summary

The protein encoded by this gene is a member of the oligameric minichromosome maintenance protein complex. During DNA replication, the complex loads onto chromatin in early G1 and is converted into an active replicative helicase during S phase. It functions to limit DNA synthesis to once per cell cycle. During embryogenesis, the encoded protein is negatively regulated through expression of paired box protein Pax 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Mcm5 Products(2)

mRNA	Protein	Name
NM_001302540.1	NP_001289469.1	DNA replication licensing factor MCM5
NM_008566.3	NP_032592.2	DNA replication licensing factor MCM5

Protein Preferred Names

Protein Names

DNA replication licensing factor MCM5

CDC46 homolog	mini chromosome maintenance deficient 5
minichromosome maintenance deficient 5, cell division cycle 46

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-153100A	(S)-mchm5U		98.87%	Unkown
HY-RS08238	MCM5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22230	Mcm5 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28752	Mcm5 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mcm5	NCBI	NCBI:4174

Name
Email *

	Sorry, but the email address you supplied was invalid.