2. Gene
  3. Mark3 - MAP/microtubule affinity regulating kinase 3 Gene

Mark3 - MAP/microtubule affinity regulating kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ETK1; Emk2; ETK-1; MPK10; C-TAK1; 1600015G02Rik; A430080F22Rik

Gene ID: 17169 | Gene type: protein coding

About Mark3

Summary

Predicted to enable protein serine/threonine kinase activity and tau-protein kinase activity. Predicted to be involved in several processes, including negative regulation of hippo signaling; peptidyl-serine autophosphorylation; and positive regulation of protein binding activity. Predicted to act upstream of or within phosphorylation. Predicted to be located in dendrite. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Human ortholog(s) of this gene implicated in visual impairment and progressive phthisis bulbi. Orthologous to human MARK3 (microtubule affinity regulating kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Mark3 Products(4)

mRNA Protein Name
NM_001370744.1 NP_001357673.1 MAP/microtubule affinity-regulating kinase 3 isoform 3
NM_001370745.1 NP_001357674.1 MAP/microtubule affinity-regulating kinase 3 isoform 4
NM_021516.4 NP_067491.2 MAP/microtubule affinity-regulating kinase 3 isoform 1
NM_022801.4 NP_073712.2 MAP/microtubule affinity-regulating kinase 3 isoform 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
28087714 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

MAP/microtubule affinity-regulating kinase 3

ELKL motif kinase 2

EMK-2

EMK2/MARK3 serine-threonine protein kinase

MPK-10

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120877 MRT199665 99.74% Unkown
HY-139604 PCC0208017 99.56% Unkown
HY-120877A (R)-MRT199665 98.70% Unkown
HY-RS08151 MARK3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17916 Mark3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24385 Mark3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mark3 NCBI NCBI:4140