2. Gene
  3. NLRP6 - Nlrp6 NLR family, pyrin domain containing 6 Gene

NLRP6 - Nlrp6 NLR family, pyrin domain containing 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Avr; Navr; Nalp6; Non-AVR; Navr/Avr

Gene ID: 171390 | Gene type: protein coding

About NLRP6

Summary

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. [provided by RefSeq, Feb 2013]

NLRP6 Products(1)

mRNA Protein Name
NM_134375.5 NP_599202.4 NACHT, LRR and PYD domains-containing protein 6
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables peptide binding IMP
IMP: Inferred from mutant phenotype
7489366 RGD
enables vasopressin receptor activity IDA
IDA: Inferred from direct assay
18413781 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NACHT, LRR and PYD domains-containing protein 6

NACHT, LRR and PYD domains-containing protein 6-like

NACHT, leucine rich repeat and PYD containing 6

angiotensin II/vasopressin receptor

dual angiotensin II/vasopressin receptor

non-angiotensin-vasopressin receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09362 NLRP6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17708 Nlrp6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24173 Nlrp6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NLRP6 NCBI NCBI:171389