2. Gene
  3. Cs - citrate synthase Gene

Cs - citrate synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 170587 | Gene type: protein coding

About Cs

Summary

Enables citrate (Si)-synthase activity. Involved in acetyl-CoA metabolic process; carboxylic acid metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Orthologous to human CS (citrate synthase). [provided by Alliance of Genome Resources, Apr 2022]

Cs Products(1)

mRNA Protein Name
NM_130755.1 NP_570111.1 citrate synthase, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables citrate (Si)-synthase activity IDA
IDA: Inferred from direct assay
818082 RGD
Biological Process GO Annotation Evidence Reference Source
involved in acetyl-CoA metabolic process IDA
IDA: Inferred from direct assay
818082 RGD
involved in citrate metabolic process IDA
IDA: Inferred from direct assay
818082 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
14984324 RGD
involved in oxaloacetate metabolic process IDA
IDA: Inferred from direct assay
818082 RGD
involved in tricarboxylic acid cycle IDA
IDA: Inferred from direct assay
9712727 RGD
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
15809022 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

citrate synthase, mitochondrial

citrate (Si)-synthase

Related Agents

Approval
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109015 Tucidinostat Inhibitor 98.60% Unkown
HY-50935 Troglitazone 99.78% Unkown
HY-B0165A Pravastatin sodium 99.38% Yes
HY-16276 Osilodrostat Inhibitor 99.90% Yes
HY-100471 Esaxerenone Antagonist 99.93% Unkown
HY-17005 Olmesartan medoxomil Inhibitor 99.67% Unkown
HY-B0023 Azelnidipine Inhibitor 99.66% Unkown
HY-14818A Laninamivir octanoate Inhibitor 98.57% Unkown
HY-N7101 Cefpodoxime Proxetil Inhibitor 98.15% Unkown
HY-16276A Osilodrostat phosphate Inhibitor 99.35% Yes
HY-B0165 Pravastatin / Unkown
HY-B1595 Cefmetazole Inhibitor 98.82% Unkown
Clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Phase
HY-124526 Chiauranib Inhibitor 99.28% Phase 3
HY-16445 Sapacitabine Chemical 98.13% Phase 3
HY-100401 Pactimibe Inhibitor 99.98% Phase 3
HY-100401A Pactimibe sulfate Inhibitor ≥98.0% Phase 3
HY-141511 Coppersensor 1 ≥98.0% Phase 2
HY-14792B Inolitazone dihydrochloride Agonist 98.86% Phase 2
HY-106888A CS-722 / Phase 2
HY-137005 CS1 / Phase 2
HY-14783 Apricoxib Inhibitor / Phase 2
HY-14792 Inolitazone Agonist / Phase 2
HY-P6306A CS-6253 TFA 98.53% Phase 1
HY-100413 CS-526 Antagonist / Phase 1
HY-145995 CS12192 Inhibitor / Phase 1
HY-19404 Embeconazole Inhibitor / Phase 1
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99758 Nofazinlimab Inhibitor 98.83% Phase 3
HY-P99270 Tigatuzumab Inducer 99.90% Phase 2
Pre-clinical Phase
Bioactive Molecules (60)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1692 L-Methionine-DL-sulfoximine Inhibitor ≥98.0% Unkown
HY-148913 CS587 Inhibitor 98.18% Unkown
HY-B0165AR Pravastatin (sodium) (Standard) 98.10% Unkown
HY-148907 CS640 Inhibitor 99.43% Unkown
HY-P6306 CS-6253 98.84% Unkown
HY-124704 Chst15-IN-1 Inhibitor 98.09% Unkown
HY-150611 EGFR-IN-70 Inhibitor 99.16% Unkown
HY-P2727 Chondroitinase ABC / Unkown
HY-134136A Octanoyl coenzyme A lithium ≥98.0% Unkown
HY-14955 Managlinat dialanetil Inhibitor 98.13% Unkown
HY-P3522A REDV TFA 99.81% Unkown
HY-116228 Cadrofloxacin Inhibitor 98.21% Unkown
HY-14180 PHA 408 Inhibitor ≥98.0% Unkown
HY-15801 HG-14-10-04 Inhibitor 99.09% Unkown
HY-P3522 REDV 98.29% Unkown
HY-105268 AzddMeC Inhibitor 98.96% Unkown
HY-108493 CS-2100 Agonist 99.12% Unkown
HY-106174 Lapisteride Inhibitor ≥99.0% Unkown
HY-106850 3′-Azido-2′,3′-dideoxyuridine Inhibitor 99.11% Unkown
HY-111640 3'-Azido-3'-deoxy-5-methylcytidine Inhibitor 99.90% Unkown
HY-50935S Troglitazone-d4 98.19% Unkown
HY-D0798 Catechol violet ≥90.0% Unkown
HY-P10948A CS-VIP 8 TFA Inhibitor / Unkown
HY-106789 Plaunotol / Unkown
HY-106888 CS-722 Free base / Unkown
HY-109015S Tucidinostat-d4 Inhibitor / Unkown
HY-123022 Tomopenem Inhibitor / Unkown
HY-133606 3,4,5-Trichlorosyringol / Unkown
HY-134136 Octanoyl Coenzyme A / Unkown
HY-134136B Octanoyl coenzyme A triammonium / Unkown
HY-143445 EGFR-IN-48 Inhibitor / Unkown
HY-14818C Laninamivir octanoate hydrate / Unkown
HY-148863 Cavα2δ1&NET-IN-2 Inhibitor / Unkown
HY-14977 CS-0777-P Agonist / Unkown
HY-159936 CS4 / Unkown
HY-160929 Linafexor Agonist / Unkown
HY-163752 CS17919 Inhibitor / Unkown
HY-169247 Pam2CS-DMAPA / Unkown
HY-169427 FRF-06-057 Inhibitor / Unkown
HY-169982 EGFR-IN-136 Inhibitor / Unkown
HY-17005R Olmesartan medoxomil (Standard) Inhibitor 99.68% Unkown
HY-17005S Olmesartan medoxomil-d6 Inhibitor / Unkown
HY-173132 AKR1Cs-IN-1 Inhibitor / Unkown
HY-19633 CS-003 Free base Antagonist / Unkown
HY-19633A CS-003 / Unkown
HY-B0023S Azelnidipine-d7 Inhibitor / Unkown
HY-B0165AS Pravastatin-13C,d3 sodium / Unkown
HY-B0165S Pravastatin-d9 sodium / Unkown
HY-P10797 TAT-N24 Inhibitor / Unkown
HY-P10948 CS-VIP 8 Inhibitor / Unkown
HY-P1816 Fibronectin CS1 Peptide / Unkown
HY-P4021 Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2 / Unkown
HY-RS03221 CS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-14955A (Rac)-Managlinat dialanetil / Unkown
HY-169481 AP-1 Degrader / Unkown
HY-B0165CS Pravastatin-d3 sodium salt 99.02% Unkown
HY-N7101S1 Cefpodoxime Proxetil-d6 Inhibitor / Unkown
HY-RS16750 Cs Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23189 Cs Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-U00211 CS476 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cs NCBI NCBI:1431
Canis familiaris Cs NCBI NCBI:474403
Macaca fascicularis Cs NCBI NCBI:101926620
Mus musculus Cs NCBI NCBI:12974
Susscrofa domestica Cs NCBI
Macaca mulatta Cs NCBI NCBI:709604