2. Gene
  3. Recql5 - RecQ protein-like 5 Gene

Recql5 - RecQ protein-like 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as RecQ5; Recq5b; Recql5b

Gene ID: 170472 | Gene type: protein coding

About Recql5

Summary

Predicted to enable DNA helicase activity; RNA polymerase II complex binding activity; and identical protein binding activity. Acts upstream of or within several processes, including cellular response to camptothecin; negative regulation of double-strand break repair via homologous recombination; and replication-born double-strand break repair via sister chromatid exchange. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of RNA polymerase II, holoenzyme. Predicted to be active in chromosome and cytoplasm. Orthologous to human RECQL5 (RecQ like helicase 5). [provided by Alliance of Genome Resources, Apr 2022]

Recql5 Products(1)

mRNA Protein Name
NM_130454.2 NP_569721.1 ATP-dependent DNA helicase Q5
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to camptothecin IGI
IGI: Inferred from genetic interaction
25520194 MGI
acts upstream of or within cellular response to camptothecin IMP
IMP: Inferred from mutant phenotype
25520194 MGI
acts upstream of or within cellular response to xenobiotic stimulus IGI
IGI: Inferred from genetic interaction
25520194 MGI
acts upstream of or within cellular response to xenobiotic stimulus IMP
IMP: Inferred from mutant phenotype
25520194 MGI
acts upstream of or within negative regulation of double-strand break repair via homologous recombination IGI
IGI: Inferred from genetic interaction
25520194 MGI
acts upstream of or within replication-born double-strand break repair via sister chromatid exchange IMP
IMP: Inferred from mutant phenotype
25520194 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-dependent DNA helicase Q5

DNA helicase, RecQ-like type 5

RECQL5beta

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-145685 RECQL5-IN-1 Inhibitor 98.40% Unkown
HY-RS11812 RECQL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17854 Recql5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24323 Recql5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Recql5 NCBI NCBI:9400