2. Gene
  3. Bbox1 - butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase) Gene

Bbox1 - butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 170442 | Gene type: protein coding

About Bbox1

Summary

Predicted to enable gamma-butyrobetaine dioxygenase activity; identical protein binding activity; and zinc ion binding activity. Predicted to be involved in carnitine biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and retina. Orthologous to human BBOX1 (gamma-butyrobetaine hydroxylase 1). [provided by Alliance of Genome Resources, Apr 2022]

Bbox1 Products(2)

mRNA Protein Name
NM_001413162.1 NP_001400091.1 gamma-butyrobetaine dioxygenase
NM_130452.2 NP_569719.1 gamma-butyrobetaine dioxygenase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables gamma-butyrobetaine dioxygenase activity IDA
IDA: Inferred from direct assay
22999781 MGI
Biological Process GO Annotation Evidence Reference Source
involved in carnitine biosynthetic process IGI
IGI: Inferred from genetic interaction
17692817 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
15535801 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gamma-butyrobetaine dioxygenase

gamma-BBH

gamma-butyrobetaine hydroxylase

gamma-butyrobetaine,2-oxoglutarate dioxygenase

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1836S Meldonium-d3 Inhibitor / Unkown
HY-RS01383 BBOX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18804 Bbox1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25293 Bbox1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bbox1 NCBI NCBI:8424