2. Gene
  3. Lamc2 - laminin, gamma 2 Gene

Lamc2 - laminin, gamma 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 16782 | Gene type: protein coding

About Lamc2

Summary

Enables heparin binding activity. Predicted to be involved in several processes, including neuron projection development; positive regulation of cell migration; and positive regulation of cell population proliferation. Predicted to act upstream of or within cell adhesion. Located in basement membrane. Part of laminin-5 complex. Is expressed in several structures, including alimentary system; basement membrane; central nervous system; genitourinary system; and skin. Used to study junctional epidermolysis bullosa Herlitz type and junctional epidermolysis bullosa non-Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Orthologous to human LAMC2 (laminin subunit gamma 2). [provided by Alliance of Genome Resources, Apr 2022]

Lamc2 Products(1)

mRNA Protein Name
NM_008485.3 NP_032511.3 laminin subunit gamma-2 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables heparin binding IDA
IDA: Inferred from direct assay
11733994 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11733994 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basement membrane IDA
IDA: Inferred from direct assay
9264260 MGI
part of laminin-5 complex IDA
IDA: Inferred from direct assay
9264260 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

laminin subunit gamma-2

epiligrin subunit gamma

kalinin subunit gamma

kalinin/nicein/epiligrin 100 kDa subunit

laminin B2t chain

laminin gamma2 chain

laminin-5 subunit gamma

nicein subunit gamma

nicein, 100kD

nicein, 100kDa

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07507 LAMC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20979 Lamc2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27496 Lamc2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lamc2 NCBI NCBI:3918