2. Gene
  3. Hspa2 - heat shock protein 2 Gene

Hspa2 - heat shock protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 70kDa; HSP70.2; HSP70A2; Hsp70-2

Gene ID: 15512 | Gene type: protein coding

About Hspa2

Summary

Enables glycolipid binding activity. Involved in positive regulation of ATPase activity; positive regulation of ATPase-coupled calcium transmembrane transporter activity; and spermatogenesis. Acts upstream of or within several processes, including male gamete generation; positive regulation of G2/M transition of mitotic cell cycle; and synaptonemal complex disassembly. Located in cell surface; meiotic spindle; and nucleus. Part of CatSper complex. Is expressed in alimentary system; ganglia; medulla oblongata basal plate; testis; and vibrissa. Orthologous to human HSPA2 (heat shock protein family A (HSP70) member 2). [provided by Alliance of Genome Resources, Apr 2022]

Hspa2 Products(4)

mRNA Protein Name
NM_001002012.2 NP_001002012.1 heat shock-related 70 kDa protein 2
NM_001409571.1 NP_001396500.1 heat shock-related 70 kDa protein 2
NM_001409572.1 NP_001396501.1 heat shock-related 70 kDa protein 2
NM_008301.5 NP_032327.2 heat shock-related 70 kDa protein 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables glycolipid binding IDA
IDA: Inferred from direct assay
9337084 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9247342 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within male meiosis I IMP
IMP: Inferred from mutant phenotype
9409676 MGI
acts upstream of or within male meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
8622925 MGI
involved in positive regulation of ATP-dependent activity IMP
IMP: Inferred from mutant phenotype
22495301 MGI
involved in positive regulation of ATPase-coupled calcium transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
22495301 MGI
acts upstream of or within positive regulation of G2/M transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
9247342 MGI
acts upstream of or within positive regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
9247342 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
8622925 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
24557841 MGI
acts upstream of or within synaptonemal complex disassembly IMP
IMP: Inferred from mutant phenotype
9409676 MGI
Cellular Component GO Annotation Evidence Reference Source
part of CatSper complex IDA
IDA: Inferred from direct assay
21224844 MGI
located in cell surface IDA
IDA: Inferred from direct assay
9337084 MGI
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
17035236 MGI
located in meiotic spindle IDA
IDA: Inferred from direct assay
24557841 MGI
located in synaptonemal complex IDA
IDA: Inferred from direct assay
8622925 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heat shock-related 70 kDa protein 2

heat shock 70kDa protein 2

heat shock protein 70.2

heat shock protein, 70 kDa 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-152153 GRP78-IN-3 Inhibitor 99.88% Unkown
HY-RS06427 HSPA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20423 Hspa2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25750 Hspa1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26932 Hspa2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hspa2 NCBI NCBI:3306