2. Gene
  3. Hoxb6 - homeobox B6 Gene

Hoxb6 - homeobox B6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hox-2.2

Gene ID: 15414 | Gene type: protein coding

About Hoxb6

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within anterior/posterior pattern specification; embryonic skeletal system morphogenesis; and erythrocyte homeostasis. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and gut. Orthologous to human HOXB6 (homeobox B6). [provided by Alliance of Genome Resources, Apr 2022]

Hoxb6 Products(1)

mRNA Protein Name
NM_008269.2 NP_032295.1 homeobox protein Hox-B6
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20211142 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
7828847 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: Inferred from mutant phenotype
7828847 MGI
acts upstream of or within embryonic skeletal system development IGI
IGI: Inferred from genetic interaction
17626057 MGI
acts upstream of or within embryonic skeletal system development IMP
IMP: Inferred from mutant phenotype
7828847 MGI
acts upstream of or within embryonic skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
10885747 MGI
acts upstream of or within erythrocyte homeostasis IMP
IMP: Inferred from mutant phenotype
10996827 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein Hox-B6

homeo box B6

homeobox protein Hox-2.2

homeobox protein MH-22A

Hoxb6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Hoxb6 P09023 Pbx1 Mus musculus P41778
Y2H Array
20211142
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06310 HOXB6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22560 Hoxb6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hoxb6 NCBI NCBI:3216