2. Gene
  3. Hdc - histidine decarboxylase Gene

Hdc - histidine decarboxylase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hdc-a; Hdc-c; Hdc-e; Hdc-s

Gene ID: 15186 | Gene type: protein coding

About Hdc

Summary

Enables histidine decarboxylase activity. Acts upstream of or within histamine biosynthetic process and histidine catabolic process. Predicted to be located in cytosol; dendrite; and neuronal cell body. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and respiratory system. Used to study Gilles de la Tourette syndrome. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; asthma; and rhinitis. Orthologous to human HDC (histidine decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

Hdc Products(1)

mRNA Protein Name
NM_008230.6 NP_032256.3 histidine decarboxylase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables histidine decarboxylase activity IMP
IMP: Inferred from mutant phenotype
11478947 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within L-histidine catabolic process IMP
IMP: Inferred from mutant phenotype
11478947 MGI
acts upstream of or within histamine biosynthetic process IMP
IMP: Inferred from mutant phenotype
11478947 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histidine decarboxylase

L-histidine decarboxylase

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W003445 4-Bromo-3-hydroxybenzoic acid 99.25% Unkown
HY-115822 α-Fluoromethylhistidine dihydrochloride Inhibitor ≥99.0% Unkown
HY-146159 PI3K/HDAC-IN-2 Inhibitor / Unkown
HY-RS06091 HDC Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W194107 Antitumor agent-152 Inhibitor / Unkown
HY-RS17727 Hdc Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24192 Hdc Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdc NCBI NCBI:3067