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1489079

" in MedChemExpress (MCE) Product Catalog:

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Recombinant Proteins

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Antibodies

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  • HY-P72259
    Protein E7, HPV16 (His)

    E7; Protein E7

    		 Virus E. coli
    HPV16 E7 is a viral phosphoprotein with oncogenic activity, belonging to the human papillomavirus early protein family. HPV16 E7 activates the cell cycle by releasing E2F through proteasome degradation of pRB. HPV16 E7 can cooperate with E6 to immortalize cells and neutralize the toxicity of E5, while activating the AP-1/NF-κB pathway and downregulating E-cadherin to enhance migration and invasion, making it a core target for cervical cancer. Protein E7, HPV (His) is a recombinant HPV E7 protein expressed from E. coli with an N-6*His tag.
  • HY-P700389
    Protein E7, HPV (N-His, C-His)

    Protein E7

    		 Virus E. coli
    HPV protein E7 can induce dormant cells to enter the cell cycle and promote the efficient use of cellular DNA replication mechanisms for viral genome replication. Through translational and transactivation activities, E7 disrupts the RB1-E2F1 complex and activates E2F1-regulated S-phase genes. Protein E7, HPV (N-His, C-His) is the recombinant Virus-derived protein E7, HPV, expressed by E. coli , with N-6*His, C-6*His labeled tag.

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