2. Gene
  3. Grk5 - G protein-coupled receptor kinase 5 Gene

Grk5 - G protein-coupled receptor kinase 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gprk5

Gene ID: 14773 | Gene type: protein coding

About Grk5

Summary

Predicted to enable beta-adrenergic receptor kinase activity and protein serine/threonine kinase activity. Involved in fat cell differentiation. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Orthologous to human GRK5 (G protein-coupled receptor kinase 5). [provided by Alliance of Genome Resources, Apr 2022]

Grk5 Products(1)

mRNA Protein Name
NM_018869.3 NP_061357.3 G protein-coupled receptor kinase 5
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18711143 MGI
Biological Process GO Annotation Evidence Reference Source
involved in fat cell differentiation IMP
IMP: Inferred from mutant phenotype
22507984 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G protein-coupled receptor kinase 5

g protein-coupled receptor kinase GRK5

Related Agents

Pre-clinical Phase
Bioactive Molecules (22)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103045 CMPD101 Inhibitor 98.95% Unkown
HY-142812 GRK6-IN-1 99.61% Unkown
HY-136561 GRK5-IN-2 Inhibitor 99.92% Unkown
HY-109562A CCG258208 hydrochloride 98.05% Unkown
HY-18991 CCG215022 Inhibitor 99.79% Unkown
HY-143248 KR-39038 Inhibitor 99.48% Unkown
HY-47573 CCG273441 Inhibitor 98.78% Unkown
HY-139690 CCG258747 Inhibitor 98.96% Unkown
HY-149720 GRL018-21 Inhibitor 96.91% Unkown
HY-108601A (S)-Ro 32-0432 Inhibitor / Unkown
HY-109562 CCG258208 Inhibitor / Unkown
HY-108601 (S)-Ro 32-0432 free base Inhibitor / Unkown
HY-118046 GSK2163632A Inhibitor / Unkown
HY-119232 GSK466317A Inhibitor / Unkown
HY-150021 GRK5-IN-3 Inhibitor / Unkown
HY-150022 GRK5-IN-4 Inhibitor / Unkown
HY-150039 CCG-271423 Inhibitor / Unkown
HY-150040 CCG-273463 Inhibitor / Unkown
HY-RS05816 GRK5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-159996 GRL093-22 Inhibitor / Unkown
HY-RS17288 Grk5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23743 Grk5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grk5 NCBI NCBI:2869