2. Gene
  3. Gnb3 - guanine nucleotide binding protein (G protein), beta 3 Gene

Gnb3 - guanine nucleotide binding protein (G protein), beta 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Hg2d; Gnb-3

Gene ID: 14695 | Gene type: protein coding

About Gnb3

Summary

Predicted to enable GTPase binding activity; signaling receptor complex adaptor activity; and spectrin binding activity. Predicted to be involved in several processes, including cell volume homeostasis; regulation of fat cell differentiation; and regulation of lipid metabolic process. Located in dendrite. Part of heterotrimeric G-protein complex. Is expressed in several structures, including eye; ganglia; gut; liver; and spleen. Human ortholog(s) of this gene implicated in artery disease (multiple); congenital stationary night blindness 1H; familial hyperlipidemia; mental depression; and type 2 diabetes mellitus. Orthologous to human GNB3 (G protein subunit beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Gnb3 Products(1)

mRNA Protein Name
NM_013530.1 NP_038558.1 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in dendrite IDA
IDA: Inferred from direct assay
12454992 MGI
part of heterotrimeric G-protein complex IPI
IPI: Inferred from physical interaction
10570481 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

heterotrimeric guanine nucleotide-binding protein 2d

transducin beta chain 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05548 GNB3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21351 Gnb3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gnb3 NCBI NCBI:2784