Slc17a6 - solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 Gene

Mus musculus

Also known as DNPI; VGLUT2; 2900073D12Rik

Gene ID: 140919 | Gene type: protein coding

About Slc17a6

Summary

Enables L-glutamate transmembrane transporter activity. Involved in hyaloid vascular plexus regression. Acts upstream of or within neurotransmitter uptake. Located in synaptic vesicle. Is expressed in several structures, including cranial ganglion; nervous system; sensory organ; tail mesenchyme; and testis. Orthologous to human SLC17A6 (solute carrier family 17 member 6). [provided by Alliance of Genome Resources, Apr 2022]

Slc17a6 Products(2)

mRNA	Protein	Name
NM_001355150.1	NP_001342079.1	vesicular glutamate transporter 2 isoform 2
NM_080853.3	NP_543129.3	vesicular glutamate transporter 2 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables L-glutamate uniporter activity	IDA IDA: Inferred from direct assay	11432869	MGI
enables potassium:proton antiporter activity	IDA IDA: Inferred from direct assay	25433636	MGI
enables sodium:phosphate symporter activity	IDA IDA: Inferred from direct assay	33440152	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in L-glutamate transmembrane transport	IMP IMP: Inferred from mutant phenotype	11432869	MGI
involved in hyaloid vascular plexus regression	IMP IMP: Inferred from mutant phenotype	30936473	MGI
acts upstream of or within neurotransmitter uptake	IDA IDA: Inferred from direct assay	11432869	MGI
involved in phosphate ion homeostasis	IDA IDA: Inferred from direct assay	33440152	MGI
involved in sodium-dependent phosphate transport	IDA IDA: Inferred from direct assay	33440152	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in presynapse	IDA IDA: Inferred from direct assay	29465786	MGI
located in synaptic vesicle	IDA IDA: Inferred from direct assay	11432869	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

vesicular glutamate transporter 2

differentiation-associated BNPI	differentiation-associated Na(+)-dependent inorganic phosphate cotransporter
solute carrier family 17 (vesicular glutamate transporter), member 6	solute carrier family 17 member 6

Slc17a6 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P87139	VGLUT2 Antibody (YA6832)	WB, IHC-F, IHC-P	Mouse, Rat

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13039	SLC17A6 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc17a6	NCBI	NCBI:57084

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