2. Gene
  3. Eef2k - eukaryotic elongation factor-2 kinase Gene

Eef2k - eukaryotic elongation factor-2 kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as eEF-2K

Gene ID: 13631 | Gene type: protein coding

About Eef2k

Summary

Enables Calmodulin binding activity and elongation factor-2 kinase activity. Involved in regulation of protein autophosphorylation. Predicted to be located in dendritic spine and postsynaptic density. Is expressed in liver; lung; nervous system; and olfactory epithelium. Orthologous to human EEF2K (eukaryotic elongation factor 2 kinase). [provided by Alliance of Genome Resources, Apr 2022]

Eef2k Products(10)

mRNA Protein Name
NM_001267710.2 NP_001254639.1 eukaryotic elongation factor 2 kinase isoform a
NM_001267711.2 NP_001254640.1 eukaryotic elongation factor 2 kinase isoform a
NM_001412328.1 NP_001399257.1 eukaryotic elongation factor 2 kinase isoform a
NM_001412329.1 NP_001399258.1 eukaryotic elongation factor 2 kinase isoform a
NM_001412330.1 NP_001399259.1 eukaryotic elongation factor 2 kinase isoform a
NM_001412331.1 NP_001399260.1 eukaryotic elongation factor 2 kinase isoform b
NM_001412332.1 NP_001399261.1 eukaryotic elongation factor 2 kinase isoform c
NM_001412333.1 NP_001399262.1 eukaryotic elongation factor 2 kinase isoform c
NM_001412334.1 NP_001399263.1 eukaryotic elongation factor 2 kinase isoform d
NM_007908.5 NP_031934.1 eukaryotic elongation factor 2 kinase isoform a
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables calmodulin binding IDA
IDA: Inferred from direct assay
9144159 MGI
enables elongation factor-2 kinase activity IDA
IDA: Inferred from direct assay
9144159 MGI
Biological Process GO Annotation Evidence Reference Source
involved in regulation of protein autophosphorylation IDA
IDA: Inferred from direct assay
9144159 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic elongation factor 2 kinase

calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase

eEF-2 kinase

eukaroytic elongation factor 2 kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-110096 A-484954 Inhibitor 99.34% Unkown
HY-100576 NH125 Inhibitor 99.63% Unkown
HY-146324 PROTAC eEF2K degrader-1 98.64% Unkown
HY-112393 TX-1918 Inhibitor / Unkown
HY-121828 TX-1123 Inhibitor / Unkown
HY-123024 Cefatrizine / Unkown
HY-176149 Fluoxetine-Conjugated Platinum(IV) prodrug-1 / Unkown
HY-RS04181 EEF2K Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20013 Eef2k Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26516 Eef2k Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eef2k NCBI NCBI:29904