1. Gene
  2. Ebf3 - early B cell factor 3 Gene

Ebf3 - early B cell factor 3 Gene

Mus musculus

Also known as O/E-2; mKIAA4201; 3110018A08Rik

Gene ID: 13593 | Gene type: protein coding

About Ebf3

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; future midbrain; genitourinary system; and retina. Orthologous to human EBF3 (EBF transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Ebf3 Products(3)

mRNA Protein Name
NM_001113414.1 NP_001106885.1 transcription factor COE3 isoform 2
NM_001113415.1 NP_001106886.1 transcription factor COE3 isoform 1
NM_010096.3 NP_034226.1 transcription factor COE3 isoform 3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12139918 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12139918 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12139918 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12139918 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12139918 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor COE3

EBF-3

OE-2

Olf-1/EBF-like 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Ebf3 NCBI NCBI:253738