2. Gene
  3. Defb1 - defensin beta 1 Gene

Defb1 - defensin beta 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as BD-1

Gene ID: 13214 | Gene type: protein coding

About Defb1

Summary

Predicted to enable CCR6 Chemokine Receptor binding activity and identical protein binding activity. Involved in innate immune response and response to bacterium. Predicted to be located in microvesicle and sperm midpiece. Predicted to be extrinsic component of membrane. Predicted to be active in extracellular space. Is expressed in epidermis and skin. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and lung disease. Orthologous to human DEFB1 (defensin beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Defb1 Products(1)

mRNA Protein Name
NM_007843.3 NP_031869.1 beta-defensin 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in innate immune response IMP
IMP: Inferred from mutant phenotype
12010999 MGI
involved in response to bacterium IMP
IMP: Inferred from mutant phenotype
12010999 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-defensin 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W074890 Palmitoylglycine Modulator 99.74% Unkown
HY-RS03678 DEFB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18060 Defb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24535 Defb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Defb1 NCBI NCBI:1672
Rattus norvegicus Defb1 NCBI NCBI:83687