2. Gene
  3. Ctsg - cathepsin G Gene

Ctsg - cathepsin G Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as VSP; CatG

Gene ID: 13035 | Gene type: protein coding

About Ctsg

Summary

This gene encodes a member of the peptidase S1 (chymotrypsin) family of serine endopeptidases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product appears to play a role in host defense, including inflammation and antigen processing. Homozygous knockout mice for this gene exhibit enhanced susceptibility to Bacterial and fungal Infection. [provided by RefSeq, Aug 2015]

Ctsg Products(1)

mRNA Protein Name
NM_007800.2 NP_031826.1 cathepsin G preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12189154 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
11907569 MGI
acts upstream of or within defense response to fungus IGI
IGI: Inferred from genetic interaction
10714686 MGI
acts upstream of or within defense response to fungus IMP
IMP: Inferred from mutant phenotype
10714686 MGI
acts upstream of or within neutrophil-mediated killing of gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
11907569 MGI
acts upstream of or within positive regulation of immune response IGI
IGI: Inferred from genetic interaction
10714686 MGI
acts upstream of or within positive regulation of immune response IMP
IMP: Inferred from mutant phenotype
10714686 MGI
acts upstream of or within response to lipopolysaccharide IGI
IGI: Inferred from genetic interaction
10714686 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
10714686 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cathepsin G

vimentin-specific protease

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03335 CTSG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18346 Ctsg Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24825 Ctsg Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctsg NCBI NCBI:1511