Bach1 - BTB and CNC homology 1, basic leucine zipper transcription factor 1 Gene

Mus musculus

Also known as 6230421P05Rik

Gene ID: 12013 | Gene type: protein coding

About Bach1

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Orthologous to human BACH1 (BTB domain and CNC homolog 1). [provided by Alliance of Genome Resources, Apr 2022]

Bach1 Products(1)

mRNA	Protein	Name
NM_007520.2	NP_031546.1	transcription regulator protein BACH1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	8887638	MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	8887638	MGI
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	8887638	MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	8887638	MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	8887638	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	8887638	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	8887638	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	8887638	MGI
acts upstream of or within regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	8887638	MGI
involved in regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	19170764	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	8887638	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

transcription regulator protein BACH1

BTB and CNC homolog 1

BTB and CNC homology 1 transcription factor

Related Agents

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-153040	HPPE	Inhibitor	99.67%	Unkown
HY-111827	S-1-Propenyl-L-cysteine		99.91%	Unkown
HY-167874	ASP-8731		98.42%	Unkown
HY-W583212	Zn(II) Mesoporphyrin IX		≥95.0%	Unkown
HY-RS01339	BACH1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS01623	BRIP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS17026	Bach1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20866	Brip1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23469	Bach1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bach1	NCBI	NCBI:571

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