Auh - AU RNA binding protein/enoyl-coenzyme A hydratase Gene

Mus musculus

Gene ID: 11992 | Gene type: protein coding

About Auh

Summary

Enables RNA binding activity and enoyl-CoA hydratase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to act upstream of or within branched-chain amino acid catabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 1 and renal tubular transport disease. Orthologous to human AUH (AU RNA binding methylglutaconyl-CoA hydratase). [provided by Alliance of Genome Resources, Apr 2022]

Auh Products(1)

mRNA	Protein	Name
NM_016709.2	NP_057918.2	methylglutaconyl-CoA hydratase, mitochondrial precursor

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA binding	IDA IDA: Inferred from direct assay	10072761	MGI
enables enoyl-CoA hydratase activity	IDA IDA: Inferred from direct assay	10072761	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrion	IDA IDA: Inferred from direct assay	10072761	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

methylglutaconyl-CoA hydratase, mitochondrial

3-MG-CoA hydratase	AU-binding enoyl-CoA hydratase
AU-specific RNA-binding enoyl-CoA hydratase	itaconyl-CoA hydratase
muAUH

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01263	AUH Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS18112	Auh Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24586	Auh Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Auh	NCBI	NCBI:549

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