2. Gene
  3. Hrk - harakiri, BCL2 interacting protein Gene

Hrk - harakiri, BCL2 interacting protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Dp5; Bid3

Gene ID: 117271 | Gene type: protein coding

About Hrk

Summary

Involved in apoptotic process; cellular response to potassium ion starvation; and positive regulation of neuron apoptotic process. Predicted to be integral component of membrane. Predicted to be active in mitochondrion. Orthologous to human HRK (harakiri, BCL2 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Hrk Products(1)

mRNA Protein Name
NM_057130.5 NP_476471.1 activator of apoptosis harakiri
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10075695 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to potassium ion starvation IMP
IMP: Inferred from mutant phenotype
17428807 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
17428807 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

activator of apoptosis harakiri

BH3 interacting (with BCL2 family) domain, apoptosis agonist

BH3 interacting domain 3

BH3-interacting domain-containing protein 3

harakiri, BCL2 interacting protein (contains only BH3 domain)

neuronal death protein DP5

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P5342 Hrk BH3 / Unkown
HY-RS06371 HRK Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS07147 KCNJ4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21284 Hrk Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27803 Hrk Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hrk NCBI NCBI:8739