2. Gene
  3. Vip - vasoactive intestinal peptide Gene

Vip - vasoactive intestinal peptide Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as vip/phi27

Gene ID: 117064 | Gene type: protein coding

About Vip

Summary

Enables hormone activity. Involved in several processes, including negative regulation of smooth muscle cell proliferation; positive regulation of endothelial cell proliferation; and positive regulation of penile erection. Located in neuronal cell body. Used to study several diseases, including Parkinsonism; brain ischemia; periodontitis; pulmonary hypertension; and uveitis. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in pulmonary sarcoidosis. Orthologous to human VIP (vasoactive intestinal peptide). [provided by Alliance of Genome Resources, Apr 2022]

Vip Products(1)

mRNA Protein Name
NM_053991.1 NP_446443.1 VIP peptides preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables hormone activity IDA
IDA: Inferred from direct assay
9603988 RGD
enables signaling receptor binding IDA
IDA: Inferred from direct assay
1314625 RGD
Biological Process GO Annotation Evidence Reference Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
9603988 RGD
involved in learning or memory IDA
IDA: Inferred from direct assay
19465061 RGD
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
21850490 RGD
involved in negative regulation of potassium ion transport IDA
IDA: Inferred from direct assay
20699230 RGD
involved in negative regulation of smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
20452385 RGD
involved in positive regulation of endothelial cell proliferation IDA
IDA: Inferred from direct assay
19332106 RGD
involved in positive regulation of penile erection IDA
IDA: Inferred from direct assay
21166748 RGD
involved in positive regulation of protein catabolic process IDA
IDA: Inferred from direct assay
9603988 RGD
involved in regulation of protein localization IDA
IDA: Inferred from direct assay
9603988 RGD
Cellular Component GO Annotation Evidence Reference Source
located in neuronal cell body IDA
IDA: Inferred from direct assay
22108610 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

VIP peptides

vasoactive intestinal polypeptide

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0012 Aviptadil Inhibitor 99.87% Unkown
HY-P0012A Aviptadil acetate Inhibitor 99.87% Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-103019B (-)-Enitociclib 99.85% Phase 1
HY-103019E Enitociclib / Phase 1
Pre-clinical Phase
Bioactive Molecules (36)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0221 PACAP (1-38), human, ovine, rat 99.88% Unkown
HY-103019 (+)-Enitociclib 99.89% Unkown
HY-P0220A PACAP (6-38), human, ovine, rat TFA 98.76% Unkown
HY-P5005 VIPhyb 99.73% Unkown
HY-103019A (±)-Enitociclib 99.87% Unkown
HY-P1023 VIP(6-28)(human, rat, porcine, bovine) Antagonist 99.69% Unkown
HY-P4127A M65 TFA Inhibitor / Unkown
HY-P1015 VIP(Guinea pig) Ligand 98.66% Unkown
HY-P1159A [D-p-Cl-Phe6,Leu17]-VIP TFA 98.06% Unkown
HY-P4195A [K15,R16,L27]VIP(1-7)/GRF(8-27) acetate Agonist 98.58% Unkown
HY-P0221C PACAP (1-38) free acid 99.84% Unkown
HY-P4776 Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27) Antagonist 98.27% Unkown
HY-P3117 PACAP (6-27) (human, ovine, rat) Antagonist 98.89% Unkown
HY-P0220 PACAP (6-38), human, ovine, rat 99.14% Unkown
HY-P10948A CS-VIP 8 TFA Inhibitor / Unkown
HY-P4195 [K15,R16,L27]VIP(1-7)/GRF(8-27) Agonist / Unkown
HY-172680 DSPE-PEG1000-VIP / Unkown
HY-172681 DSPE-PEG2000-VIP / Unkown
HY-172682 DSPE-PEG5000-VIP / Unkown
HY-173339 VIP36 Agonist / Unkown
HY-P0211 [Ac-Tyr1,D-Phe2]GRF 1-29, amide (human) Antagonist / Unkown
HY-P0221A PACAP (1-38), human, ovine, rat TFA / Unkown
HY-P0221B PACAP (1-38) free acid TFA / Unkown
HY-P1015A VIP(Guinea pig) TFA Ligand / Unkown
HY-P10768 Ro 25-1553 Agonist / Unkown
HY-P10948 CS-VIP 8 Inhibitor / Unkown
HY-P1158 [Ala2,8,9,11,19,22,24,25,27,28]-VIP / Unkown
HY-P1159 [D-p-Cl-Phe6,Leu17]-VIP Antagonist / Unkown
HY-P1767 Prepro VIP (81-122), human / Unkown
HY-P2702 Helodormin Agonist / Unkown
HY-P3050 Helospectin II Inhibitor / Unkown
HY-P3053 Helospectin I / Unkown
HY-RS15653 VIP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-164429 VIP236 / Unkown
HY-RS16586 Vip Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23021 Vip Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vip NCBI NCBI:7432
Mus musculus Vip NCBI NCBI:22353