1. Gene
  2. Dffa - DNA fragmentation factor subunit alpha Gene

Dffa - DNA fragmentation factor subunit alpha Gene

Rattus norvegicus

Also known as ICAD-S

Gene ID: 114214 | Gene type: protein coding

About Dffa

Summary

Predicted to enable deoxyribonuclease inhibitor activity; protein domain specific binding activity; and protein folding chaperone. Predicted to be involved in chaperone-mediated protein folding; negative regulation of deoxyribonuclease activity; and negative regulation of execution phase of Apoptosis. Predicted to act upstream of or within negative regulation of apoptotic DNA fragmentation; positive regulation of apoptotic process; and thymocyte apoptotic process. Located in nucleus. Orthologous to human DFFA (DNA fragmentation factor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Dffa Products(2)

mRNA Protein Name
NM_001398977.1 NP_001385906.1 DNA fragmentation factor subunit alpha isoform 1
NM_053679.3 NP_446131.2 DNA fragmentation factor subunit alpha isoform 2
Protein Preferred Names Protein Names

DNA fragmentation factor subunit alpha

DNA fragmentation factor, alpha polypeptide

DNA fragmentation factor, alpha subunit

Orthologs Information

Species Symbol Source ID
Homo sapiens Dffa NCBI NCBI:1676