2. Gene
  3. Timp4 - tissue inhibitor of metalloproteinase 4 Gene

Timp4 - tissue inhibitor of metalloproteinase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Timp-4

Gene ID: 110595 | Gene type: protein coding

About Timp4

Summary

Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Acts upstream of or within Notch signaling pathway. Predicted to be located in sarcomere. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including brain ventricular layer; heart; ovary; skin; and ventral grey horn. Human ortholog(s) of this gene implicated in nephroblastoma. Orthologous to human TIMP4 (TIMP metallopeptidase inhibitor 4). [provided by Alliance of Genome Resources, Apr 2022]

Timp4 Products(2)

mRNA Protein Name
NM_001356406.1 NP_001343335.1 metalloproteinase inhibitor 4 isoform 2
NM_080639.4 NP_542370.3 metalloproteinase inhibitor 4 isoform 1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
23117660 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

metalloproteinase inhibitor 4

tissue inhibitor of metalloproteinases 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14541 TIMP4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20115 Timp4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26619 Timp4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Timp4 NCBI NCBI:7079