Aida - axin interactor, dorsalization associated Gene

Mus musculus

Also known as 2610208M17Rik

Gene ID: 108909 | Gene type: protein coding

About Aida

Summary

Enables protein domain specific binding activity. Involved in negative regulation of JNK cascade and negative regulation of protein-containing complex assembly. Acts upstream of or within negative regulation of JUN kinase activity and regulation of protein-containing complex assembly. Located in cytoplasm. Orthologous to human AIDA (axin interactor, dorsalization associated). [provided by Alliance of Genome Resources, Apr 2022]

Aida Products(1)

mRNA	Protein	Name
NM_181732.4	NP_859421.1	axin interactor, dorsalization-associated protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	17681137	MGI
enables protein domain specific binding	IPI IPI: Inferred from physical interaction	17681137	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of JNK cascade	IMP IMP: Inferred from mutant phenotype	17681137	MGI
involved in negative regulation of JNK cascade	IPI IPI: Inferred from physical interaction	17681137	MGI
acts upstream of or within negative regulation of JUN kinase activity	IDA IDA: Inferred from direct assay	17681137	MGI
acts upstream of or within negative regulation of JUN kinase activity	IMP IMP: Inferred from mutant phenotype	17681137	MGI
NOT involved in negative regulation of Wnt signaling pathway	IMP IMP: Inferred from mutant phenotype	17681137	MGI
involved in negative regulation of protein-containing complex assembly	IMP IMP: Inferred from mutant phenotype	17681137	MGI
acts upstream of or within regulation of protein-containing complex assembly	IMP IMP: Inferred from mutant phenotype	17681137	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	17681137	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

axin interactor, dorsalization-associated protein

axin interaction partner and dorsalization antagonist

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-101311	UPF-523	Antagonist	99.89%	Phase 4

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00489	AIDA Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS18335	Aida Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24814	Aida Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Aida	NCBI	NCBI:64853

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