2. Gene
  3. Tnfaip8 - tumor necrosis factor, alpha-induced protein 8 Gene

Tnfaip8 - tumor necrosis factor, alpha-induced protein 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Nded; Tipe; Gg2-1; Ssc-2; Gm10539; E130304C20Rik

Gene ID: 106869 | Gene type: protein coding

About Tnfaip8

Summary

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Acts upstream of or within defense response to Gram-positive bacterium. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including brain ventricular layer; choroid plexus; musculoskeletal system; respiratory system; and thymus primordium. Orthologous to human TNFAIP8 (TNF alpha induced protein 8). [provided by Alliance of Genome Resources, Apr 2022]

Tnfaip8 Products(4)

mRNA Protein Name
NM_001177759.1 NP_001171230.1 tumor necrosis factor alpha-induced protein 8 isoform 2
NM_001177760.1 NP_001171231.1 tumor necrosis factor alpha-induced protein 8 isoform 3
NM_001360935.1 NP_001347864.1 tumor necrosis factor alpha-induced protein 8 isoform 4
NM_134131.2 NP_598892.2 tumor necrosis factor alpha-induced protein 8 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables molecular sequestering activity EXP
EXP: Inferred from Experiment
28740220 MGI
enables small molecule binding EXP
EXP: Inferred from Experiment
28740220 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
20824097 MGI
acts upstream of or within interleukin-1 beta production IMP
IMP: Inferred from mutant phenotype
20824097 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor alpha-induced protein 8

TNF alpha-induced protein 8

TNF-induced protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14791 TNFAIP8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14792 TNFAIP8L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14793 TNFAIP8L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14794 TNFAIP8L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19287 Tnfaip8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25777 Tnfaip8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfaip8 NCBI NCBI:25816