2. Gene
  3. Kmt2b - lysine methyltransferase 2B Gene

Kmt2b - lysine methyltransferase 2B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mll4; Wbp7; RGD1308331

Gene ID: 102550344 | Gene type: protein coding

About Kmt2b

Summary

Predicted to enable Histone Methyltransferase activity (H3-K4 specific); unmethylated CpG binding activity; and zinc ion binding activity. Predicted to be involved in histone H3-K4 dimethylation; histone H3-K4 monomethylation; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including DNA methylation-dependent heterochromatin assembly; female gamete generation; and histone H3-K4 trimethylation. Predicted to be located in nucleus. Predicted to be part of Histone Methyltransferase complex. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma; dystonia; and hepatocellular carcinoma. Orthologous to human KMT2B (lysine methyltransferase 2B). [provided by Alliance of Genome Resources, Apr 2022]

Kmt2b Products(3)

mRNA Protein Name
XM_039093869.1 XP_038949797.1 histone-lysine N-methyltransferase 2B isoform X1
XM_008759254.3 XP_008757476.1 histone-lysine N-methyltransferase 2B isoform X2
XM_039093878.1 XP_038949806.1 histone-lysine N-methyltransferase 2B isoform X3
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase 2B

WW domain binding protein 7

histone-lysine N-methyltransferase 2B-like

lysine (K)-specific methyltransferase 2B

myeloid/lymphoid or mixed-lineage leukemia 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07402 KMT2B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20975 Kmt2b Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27492 Kmt2b Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kmt2b NCBI NCBI:9757