2. Gene
  3. Nt5c2 - 5'-nucleotidase, cytosolic II Gene

Nt5c2 - 5'-nucleotidase, cytosolic II Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 100363253 | Gene type: protein coding

About Nt5c2

Summary

Enables 5'-nucleotidase activity. Involved in IMP metabolic process and adenosine metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II). [provided by Alliance of Genome Resources, Apr 2022]

Nt5c2 Products(1)

mRNA Protein Name
NM_001401711.1 NP_001388640.1 cytosolic purine 5'-nucleotidase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables 5'-nucleotidase activity IDA
IDA: Inferred from direct assay
6260203 RGD
enables GMP 5'-nucleotidase activity IDA
IDA: Inferred from direct assay
6260203 RGD
enables IMP 5'-nucleotidase activity IDA
IDA: Inferred from direct assay
6260203 RGD
Biological Process GO Annotation Evidence Reference Source
involved in GMP metabolic process IDA
IDA: Inferred from direct assay
6260203 RGD
involved in IMP metabolic process IDA
IDA: Inferred from direct assay
6260203 RGD
involved in adenosine metabolic process IDA
IDA: Inferred from direct assay
12675911 RGD
involved in dGMP metabolic process IDA
IDA: Inferred from direct assay
6260203 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytosolic purine 5'-nucleotidase

cytosolic nucleoside phosphotransferase 5'N

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-167710 CRCD2 99.02% Unkown
HY-RS09609 NT5C2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09610 NT5DC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21673 Nt5c2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28191 Nt5c2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nt5c2 NCBI NCBI:22978