2. Gene
  3. Kmt2d - lysine methyltransferase 2D Gene

Kmt2d - lysine methyltransferase 2D Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mll2

Gene ID: 100362634 | Gene type: protein coding

About Kmt2d

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Predicted to be involved in several processes, including histone H3-K4 methylation; positive regulation of intracellular Estrogen receptor signaling pathway; and regulation of gene expression. Predicted to act upstream of or within in utero embryonic development and regulation of gene expression. Predicted to be part of MLL3/4 complex. Human ortholog(s) of this gene implicated in Kabuki syndrome and esophagus squamous cell carcinoma. Orthologous to human KMT2D (lysine methyltransferase 2D). [provided by Alliance of Genome Resources, Apr 2022]

Kmt2d Products(4)

mRNA Protein Name
XM_017595321.2 XP_017450810.1 histone-lysine N-methyltransferase 2D isoform X1
XM_008765859.3 XP_008764081.1 histone-lysine N-methyltransferase 2D isoform X2
XM_039080567.1 XP_038936495.1 histone-lysine N-methyltransferase 2D isoform X4
XM_039080566.1 XP_038936494.1 histone-lysine N-methyltransferase 2D isoform X3
Protein Preferred Names Protein Names

histone-lysine N-methyltransferase 2D

lysine (K)-specific methyltransferase 2D

myeloid/lymphoid or mixed-lineage leukemia 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07404 KMT2D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17767 Kmt2d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24234 Kmt2d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kmt2d NCBI NCBI:8085