2. Gene
  3. Abo - ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Gene

Abo - ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Abo2

Gene ID: 100301568 | Gene type: protein coding

About Abo

Summary

Enables alpha-1,3-galactosyltransferase activity and glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity. Involved in several processes, including cellular oligosaccharide metabolic process; response to nematode; and response to retinoic acid. Located in Golgi apparatus and cytoplasmic vesicle. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; gallbladder carcinoma; leukemia (multiple); lung disease (multiple); and severe acute respiratory syndrome. Orthologous to human ABO (ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Abo Products(1)

mRNA Protein Name
NM_001160263.2 NP_001153735.1 histo-blood group ABO system transferase 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables alpha-1,3-galactosyltransferase activity IDA
IDA: Inferred from direct assay
12626403 RGD
enables glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity IDA
IDA: Inferred from direct assay
11842091 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
12499407 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
12499407 RGD
involved in response to nematode IEP
IEP: Inferred from expression pattern
11842091 RGD
involved in response to retinoic acid IEP
IEP: Inferred from expression pattern
15042712 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histo-blood group ABO system transferase 2

ABO blood group (alpha 1-3-N-acetylgalactosaminyltransferase, alpha 1-3-galactosyltransferase)

ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase

ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase

trans

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-E70051 alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) / Unkown
HY-115635 ABO hydrochloride Modulator 98.7% Unkown
HY-RS00109 ABO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17181 Abo Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23632 Abo Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abo NCBI NCBI:28
Mus musculus Abo NCBI NCBI:80908