2. Gene
  3. XIAP - X-linked inhibitor of apoptosis Gene

XIAP - X-linked inhibitor of apoptosis Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa

Also known as BIRC4

Gene ID: 100037300 | Gene type: protein coding

About XIAP

Primary_assembly X: 101,399,812-101,440,013 forward strand.Sscrofa11.1:CM000830.5

This gene has 1 transcript (splice variant), 217 orthologues and 6 paralogues. Ubiquitous expression in lung (RPKM 12.6), kidney (RPKM 12.3) and 8 other tissues.

XIAP Products(1)

mRNA Protein Name
NM_001097436.1 NP_001090905.1 E3 ubiquitin-protein ligase XIAP

XIAP Protein Structure

BIR

BIR: cd00022 (45 - 112)

BIR

BIR: smart00238 (179 - 249)

BIR

BIR: smart00238 (281 - 347)

UBA_BIRC4_8

UBA_BIRC4_8: cd14395 (386 - 435)

RING-HC_BIRC4_8

RING-HC_BIRC4_8: cd16714 (450 - 513)

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  • 514 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase XIAP

baculoviral IAP repeat-containing 4

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-15454 Xevinapant Antagonist 99.94% Phase 3
HY-13208 Xevinapant hydrochloride Antagonist 98.01% Phase 3
Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12600 AZD5582 Antagonist 98.75% Unkown
HY-17473 Embelin Antagonist 98.75% Unkown
HY-110346 AZD5582 dihydrochloride Antagonist 98.67% Unkown
HY-151966 TD1092 Degrader 99.49% Unkown
HY-125378 SBP-0636457 Antagonist 98.42% Unkown
HY-102051 XIAP/cIAP1 antagonist-1 Inhibitor / Unkown
HY-100682 T-3256336 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens XIAP NCBI NCBI:331