2. Metabolic Enzyme/Protease
  3. FXR 17β-HSD
  4. FXR/HSD17B13 modulator 1

FXR/HSD17B13 modulator 1 (compound 6) is a potent modulator of FXR/HSD17B13. FXR/HSD17B13 modulator 1 plays an important roel in metabolic dysfunction-associated steatohepatitis (MASH) research.

For research use only. We do not sell to patients.

FXR/HSD17B13 modulator 1

FXR/HSD17B13 modulator 1 Chemical Structure

CAS No. : 3067566-36-0

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FXR/HSD17B13 modulator 1 Related Antibodies

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Description

FXR/HSD17B13 modulator 1 (compound 6) is a potent modulator of FXR/HSD17B13. FXR/HSD17B13 modulator 1 plays an important roel in metabolic dysfunction-associated steatohepatitis (MASH) research[1].

Molecular Weight

480.34

Formula

C26H19Cl2NO4
CAS No.
Appearance

Solid

Color

off-white

SMILES

O=C(O)C1=CC=C(C=C1)C2=CC=C(C=C2)OCC3=C(ON=C3C4=C(C=CC=C4Cl)Cl)C5CC5
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (26.02 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0819 mL 10.4093 mL 20.8186 mL
5 mM 0.4164 mL 2.0819 mL 4.1637 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0819 mL 10.4093 mL 20.8186 mL 52.0465 mL
5 mM 0.4164 mL 2.0819 mL 4.1637 mL 10.4093 mL
10 mM 0.2082 mL 1.0409 mL 2.0819 mL 5.2046 mL
15 mM 0.1388 mL 0.6940 mL 1.3879 mL 3.4698 mL
20 mM 0.1041 mL 0.5205 mL 1.0409 mL 2.6023 mL
25 mM 0.0833 mL 0.4164 mL 0.8327 mL 2.0819 mL
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FXR/HSD17B13 modulator 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FXR/HSD17B13 modulator 13067566-36-0FXR17β-HSDNR1H417beta-HSD17β-hydroxysteroid dehydrogenases17 beta-hydroxysteroid dehydrogenaseInhibitorinhibitorinhibit

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