1. Cell Cycle/DNA Damage Antibody-drug Conjugate/ADC Related
  2. Topoisomerase ADC Payload
  3. Exatecan analog 38

Exatecan analog 38 is a camptothecin derivative with potent topoisomerase I inhibitory activity. Exatecan analog 38 can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan analog 38 can be used for cancer research.

For research use only. We do not sell to patients.

Exatecan analog 38

Exatecan analog 38 Chemical Structure

CAS No. : 2766214-00-8

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Description

Exatecan analog 38 is a camptothecin derivative with potent topoisomerase I inhibitory activity. Exatecan analog 38 can be connected to monoclonal antibodies via linkers to form antibody-drug conjugate (ADC) molecules. Exatecan analog 38 can be used for cancer research[1].

Molecular Weight

619.64

Formula

C32H34FN5O7

CAS No.
SMILES

O=C([C@H]1C[C@@H](C1)OCNC(CN)=O)N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Exatecan analog 38
Cat. No.:
HY-178315
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