2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. EVT-101 free base

EVT-101 free base is a GluN2B antagonist. EVT-101 free base binds at the same GluN1/GluN2B dimer interface as Ifenprodil (HY-12882). EVT-101 free base inhibits calcium influx in chicken-derived cells, with an EC50 of 22 nM. EVT-101 can be used in the research of brain disorders.

For research use only. We do not sell to patients.

EVT-101 free base

EVT-101 free base Chemical Structure

CAS No. : 627525-33-1

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EVT-101 free base Related Antibodies

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Description

EVT-101 free base is a GluN2B antagonist. EVT-101 free base binds at the same GluN1/GluN2B dimer interface as Ifenprodil (HY-12882). EVT-101 free base inhibits calcium influx in chicken-derived cells, with an EC50 of 22 nM. EVT-101 can be used in the research of brain disorders[1][2].

Molecular Weight

318.30

Formula

C16H13F3N4
CAS No.
SMILES

CC1=NC=CN1CC2=NN=CC(C3=CC=C(F)C(C(F)F)=C3)=C2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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EVT-101 free base Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EVT-101627525-33-1ENS-101EVT101EVT 101ENS101ENS 101iGluRIonotropic glutamate receptorsGallus gallusHEK-293forebrain neuronsInhibitorinhibitorinhibit

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