Eucalbanin B  (Synonyms: Cornusiin A)

Eucalbanin B (Cornusiin A) is a dimeric tannic acid. Eucalbanin B inhibits 5α-reductase and reduces the production of dihydrotestosterone (DHT). Eucalbanin B has anti-inflammatory properties and can inhibit the production of key pro-inflammatory cytokines (IL-6, IL-8, IL-1β, TNF-α). Eucalbanin B has a strong inhibitory effect on the proliferation of benign prostatic hyperplasia (BPH) cell lines and can induce apoptosis in BPH cells. Eucalbanin B can be used for research on BPH^[1][2].

1571.10

C₆₈H₅₀O₄₄

95263-69-7

OC1=CC(C(OC[C@@H]2[C@H]([C@H](OC(C3=CC(O)=C(O)C(O)=C3)=O)[C@@H](OC(C4=CC(O)=C(O)C(O)=C4OC5=CC(C(OC[C@@H]6[C@@H]7[C@H](OC(C8=CC(O)=C(O)C(O)=C8)=O)[C@H](C(O)O6)OC(C9=CC(O)=C(O)C(O)=C9)=O)=O)=C(C%10=C(O)C(O)=C(O)C=C%10C(O7)=O)C(O)=C5O)=O)C(O)O2)O%11)=O)=C(C%12=C(O)C(O)=C(O)C=C%12C%11=O)C(O)=C1O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Park DH, et al. Inhibitory Activities of Dimeric Ellagitannins Isolated from Cornus alba on Benign Prostatic Hypertrophy. Molecules. 2021 Jun 6;26(11):3446.

  [2]. Yoshida T, et al. Chemical and Biological Significance of Oenothein B and Related Ellagitannin Oligomers with Macrocyclic Structure. Molecules. 2018 Mar 2;23(3):552.