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  3. PPAR
  4. ESP-31015

ESP-31015 (ETC-1001) is an orally active and non-fibrate based PPARα agonists. ESP-31015 demonstrates significant lipid-regulating effects in the obese Zucker rat model. ESP-31015 can be used in cardiovascular disease research.

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ESP-31015

ESP-31015 Chemical Structure

CAS No. : 413624-55-2

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ESP-31015 Related Antibodies

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Description

ESP-31015 (ETC-1001) is an orally active and non-fibrate based PPARα agonists. ESP-31015 demonstrates significant lipid-regulating effects in the obese Zucker rat model. ESP-31015 can be used in cardiovascular disease research[1].

IC50 & Target[1]

PPARα

 

In Vivo

ESP-31015 (100 mg/kg, p.o., once daily for 2 weeks) shows a 34.6% increase in serum HDL-cholesterol and a 71% reduction in serum triglycerides in female obese Zucker fatty rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female obese Zucker fatty rats model[1]
Dosage: 100 mg/kg
Administration: Oral administration (p.o.), once daily for 2 weeks
Result: Showed a 34.6% increase in serum HDL-cholesterol and a 71% reduction in serum triglycerides.
Molecular Weight

286.45

Formula

C17H34O3
CAS No.
SMILES

OCC(C)(C)CCCCC(CCCCC(C)(C)CO)=O
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Room temperature in continental US; may vary elsewhere.
Storage

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Purity & Documentation
References
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ESP-31015 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ESP-31015413624-55-2ETC-1001ESP31015ESP 31015ETC1001ETC 1001PPARPeroxisome proliferator-activated receptorsHDL elevatorsHDL mimeticsreverse cholesterol transport (RCT)PPARα agonistsCETP inhibitorsApoA-I mimeticsatherosclerosis therapeuticsdyslipidemia treatmentInhibitorinhibitorinhibit

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