2. Fluorescent Dye
  3. Ion Fluorescent Indicators

Ion Fluorescent Indicators

Ions exhibit differential distribution inside and outside the cell, forming the basis for maintaining cellular electrochemical homeostasis and signal transduction. Imbalances in ion homeostasis are closely associated with various pathophysiological processes mediated by electrophysiological activity.Ion Fluorescent Probes, as highly sensitive and fast-responding detection tools, can monitor real-time changes in ion concentration and localization.They are commonly applied in studies of membrane potential dynamics, spatiotemporal ion homeostasis and related cellular processes. The fluorescent stock solutions are easy to use with minimized reagent loss, while ensuring experimental reproducibility.

Ion Fluorescent Indicators (4):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-DY1055
    TSQ (solution) 109628-27-5
    TSQ (solution) is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn2+ in the presence of Ca2+ and Mg2+ to produce blue fluorescence (Ex/Em = 334/495 nm).
    Solution Concentration: 10 mM
    TSQ (solution)
  • HY-DY1028
    Fluo-4 AM (solution) 273221-67-3
    Fluo-4 AM (solution) is a cell-permeable Ca2+ (calcium ion) indicator (Ex/Em = 485/526 nm).
    Solution Concentration: 1 mM
    Fluo-4 AM (solution)
  • HY-DY1030
    RhoNox-1 (solution) 1447815-38-4
    RhoNox-1 (solution) is a fluorescent probe for the specific detection of divalent iron ions, and when RhoNox-1 reacts with Fe2+. RhoNox-1 can generate an irreversible orange (red) fluorescent product (Ex/Em：540/575 nm) . FeRhoNox-1 can enter the cell well, suitable for the detection of Fe2+ in living cells, and tends to be localized in the Golgi apparatus.
    Solution Concentration: 5 mM
    RhoNox-1 (solution)
  • HY-DY1020
    Rhod-2 AM (solution) 145037-81-6
    Rhod-2 (solution) is a high-affinity visible light excitation wavelength Ca2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm.
    Solution Concentration: 1 mM
    Rhod-2 AM (solution)