2. Anti-infection Metabolic Enzyme/Protease
  3. HIV Protease HIV
  4. DMP-851

DMP-851 is a cyclic urea HIV protease inhibitor, with a Ki of 0.021 nM. DMP-851 shows antiviral activity against laboratory strains of HIV-l and HIV-2 as well as against primary clinical isolates derived from Zidovudine (HY-17413)-resistant samples (A018C, E, WR 10983).

For research use only. We do not sell to patients.

DMP-851

DMP-851 Chemical Structure

CAS No. : 188978-02-1

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DMP-851 Related Antibodies

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Description

DMP-851 is a cyclic urea HIV protease inhibitor, with a Ki of 0.021 nM. DMP-851 shows antiviral activity against laboratory strains of HIV-l and HIV-2 as well as against primary clinical isolates derived from Zidovudine (HY-17413)-resistant samples (A018C, E, WR 10983)[1].

IC50 & Target[1]

HIV-1

 

HIV-2

 

Molecular Weight

527.66

Formula

C31H37N5O3
CAS No.
SMILES

O=C1N(CC2=CC3=C(NN=C3N)C=C2)[C@H](CC4=CC=CC=C4)[C@H](O)[C@@H](O)[C@@H](CC5=CC=CC=C5)N1CCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DMP-851 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DMP-851188978-02-1DMP851DMP 851HIV ProteaseHIVHuman immunodeficiency virusHIV-lHIV-2antiviralInhibitorinhibitorinhibit

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