2. GPCR/G Protein Neuronal Signaling Membrane Transporter/Ion Channel
  3. Adrenergic Receptor Sodium Channel
  4. DL-017

DL-017 is a Quinazoline derivative. DL-017 shows inhibitory constants of approximately 0.90 nM for α1-adrenergic receptors and 404 nM for Na+ channels. DL-017 exerts antihypertensive effect.

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DL-017

DL-017 Chemical Structure

CAS No. : 149847-79-0

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DL-017 Related Antibodies

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Description

DL-017 is a Quinazoline derivative. DL-017 shows inhibitory constants of approximately 0.90 nM for α1-adrenergic receptors and 404 nM for Na+ channels. DL-017 exerts antihypertensive effect[1].

IC50 & Target[1]

α1-adrenergic receptor

 

Molecular Weight

421.56

Formula

C23H27N5OS
CAS No.
SMILES

CSC1=NC2=C(C=CC=C2)C3=NCC(CN4CCN(C5=CC=CC=C5OC)CC4)N13
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
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DL-017 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-017149847-79-0DL017DL 017Adrenergic ReceptorSodium ChannelBeta ReceptorNa channelsNa+ channelsspontaneously hypertensive ratsantihypertensiveInhibitorinhibitorinhibit

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