2. Disease Areas
  3. Infection
  4. Coronavirus Infection
  5. hCoV-OC43

hCoV-OC43

hCoV-OC43 is a seasonal coronavirus that mainly replicates in the epithelial cells of the upper respiratory tract, usually causing mild to moderate common cold-like symptoms, though it can occasionally result in severe complications such as pneumonia and central nervous system infections.

hCoV-OC43 (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-157805
    PROTAC SARS-CoV-2 Mpro degrader-2 3057294-32-0
    PROTAC SARS-CoV-2 Mpro degrader-2 (Compound 6) is a potent PROTAC degrader of SARS-CoV-2 Mpro. PROTAC SARS-CoV-2 Mpro degrader-2 has broad-spectrum antiviral activity against CoVs, including SARS-CoV-2 (EC50 = 10.8 μM), HCoV-OC43 (EC50 = 1.6 μM) and HCoV-229E (EC50 = 6.5 μM). PROTAC SARS-CoV-2 Mpro degrader-2 exhibits potent activity against SARS-CoV-2 in Calu-3 cells, with an EC50 of 0.89 μM.
    PROTAC SARS-CoV-2 Mpro degrader-2