2. Disease Areas
  3. Infection
  4. Coronavirus Infection
  5. hCoV-229E

hCoV-229E

hCoV-229E is an alphacoronavirus closely related to HCoV-NL63, belonging to the subfamily Orthocoronavirinae, which comprises several zoonotic viruses. It commonly circulates alongside other strains and genotypes, primarily causing respiratory infections in humans.

hCoV-229E (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-157805
    PROTAC SARS-CoV-2 Mpro degrader-2 3057294-32-0
    PROTAC SARS-CoV-2 Mpro degrader-2 (Compound 6) is a potent PROTAC degrader of SARS-CoV-2 Mpro. PROTAC SARS-CoV-2 Mpro degrader-2 has broad-spectrum antiviral activity against CoVs, including SARS-CoV-2 (EC50 = 10.8 μM), HCoV-OC43 (EC50 = 1.6 μM) and HCoV-229E (EC50 = 6.5 μM). PROTAC SARS-CoV-2 Mpro degrader-2 exhibits potent activity against SARS-CoV-2 in Calu-3 cells, with an EC50 of 0.89 μM.
    PROTAC SARS-CoV-2 Mpro degrader-2