Bacillus Subtilis Infection

Bacillus subtilis infection is rare but can occur in immunocompromised individuals or following invasive procedures, with clinical manifestations ranging from localized infections to systemic disease. The bacterium's ability to form highly resistant spores enables survival under harsh conditions, contributing to its persistence in the environment and potential for nosocomial transmission. While primarily considered a non-pathogenic organism with widespread use in biotechnology, B. subtilis has been associated with opportunistic infections such as endophthalmitis, bacteremia, and pneumonia, particularly in patients with underlying health conditions or indwelling medical devices. These infections are often challenging to treat due to the inherent resistance of spores and potential antibiotic tolerance of biofilm-forming strains. Early diagnosis and appropriate antimicrobial therapy are crucial for favorable outcomes.

References: