Abnormal Gastric Acid Secretion

Abnormal gastric acid secretion encompasses conditions such as gastric hyperacidity, characterized by increased acid production that typically emerges around the tenth day of life due to maturation of the gastric mucosa, and hypochlorhydria, which reflects irreversible gastric atrophy and marked intestinal metaplasia. While early-stage gastric cancers are strongly linked to H. pylori infection, this association weakens in late-stage cancers, with only about 70% or fewer cases showing active H. pylori infection, suggesting the bacterium may have been eradicated by host defenses—such as mucus production—or may have disappeared prior to cancer development, indicating that other risk factors were already established.

References:

[1]. Gastric Hypoacidity. sciencedirect.

Abnormal Gastric Acid Secretion (1):

Targets:	Histamine Receptor (1)

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-19170

Z-300	128289-57-6
Z-300 is a selective and orally active histamine H2-receptor antagonist. Z-300 inhibits acid secretion and promotes gastric mucus metabolism in the corpus region.

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