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  3. Dermocybin

Dermocybin (NSC 257450) is a natural anthraquinone isolated from the fungus Derniocybe sarzgiiirzea. Dermocybin can be used as a high-temperature disperse dye for polyester and polyamide fabrics.

For research use only. We do not sell to patients.

Dermocybin

Dermocybin Chemical Structure

CAS No. : 7229-69-8

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Description

Dermocybin (NSC 257450) is a natural anthraquinone isolated from the fungus Derniocybe sarzgiiirzea. Dermocybin can be used as a high-temperature disperse dye for polyester and polyamide fabrics[1].

Cellular Effect
Cell Line Type Value Description References
A549 EC50
16.2 μM
Compound: 5
Phototoxicity against human A549 cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by green light irradiation at 519 nm for 22 mins 23 sec and measured after 48 hrs by SRB assay
Phototoxicity against human A549 cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by green light irradiation at 519 nm for 22 mins 23 sec and measured after 48 hrs by SRB assay
[PMID: 37708055]
A549 EC50
> 25 μM
Compound: 5
Phototoxicity against human A549 cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by blue light irradiation at 468 nm for 7 mins 30 sec and measured after 48 hrs by SRB assay
Phototoxicity against human A549 cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by blue light irradiation at 468 nm for 7 mins 30 sec and measured after 48 hrs by SRB assay
[PMID: 37708055]
A549 EC50
> 25 μM
Compound: 5
Phototoxicity against human A549 cells assessed as reduction in cell growth preincubated with compound for 24 hrs under dark condition and measured after 48 hrs by SRB assay
Phototoxicity against human A549 cells assessed as reduction in cell growth preincubated with compound for 24 hrs under dark condition and measured after 48 hrs by SRB assay
[PMID: 37708055]
AGS EC50
> 25 μM
Compound: 5
Phototoxicity against human AGS cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by blue light irradiation at 468 nm for 7 mins 30 sec and measured after 48 hrs by SRB assay
Phototoxicity against human AGS cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by blue light irradiation at 468 nm for 7 mins 30 sec and measured after 48 hrs by SRB assay
[PMID: 37708055]
AGS EC50
> 25 μM
Compound: 5
Phototoxicity against human AGS cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by green light irradiation at 519 nm for 22 mins 23 sec and measured after 48 hrs by SRB assay
Phototoxicity against human AGS cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by green light irradiation at 519 nm for 22 mins 23 sec and measured after 48 hrs by SRB assay
[PMID: 37708055]
AGS EC50
> 25 μM
Compound: 5
Phototoxicity against human AGS cells assessed as reduction in cell growth preincubated with compound for 24 hrs under dark condition and measured after 48 hrs by SRB assay
Phototoxicity against human AGS cells assessed as reduction in cell growth preincubated with compound for 24 hrs under dark condition and measured after 48 hrs by SRB assay
[PMID: 37708055]
DU-145 IC50
3.93 μM
Compound: 1
Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by Alamar blue assay
Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 72 hrs by Alamar blue assay
[PMID: 27173800]
T-24 EC50
11.6 μM
Compound: 5
Phototoxicity against human T24 cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by green light irradiation at 519 nm for 22 mins 23 sec and measured after 48 hrs by SRB assay
Phototoxicity against human T24 cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by green light irradiation at 519 nm for 22 mins 23 sec and measured after 48 hrs by SRB assay
[PMID: 37708055]
T-24 EC50
24.7 μM
Compound: 5
Phototoxicity against human T24 cells assessed as reduction in cell growth preincubated with compound for 24 hrs under dark condition and measured after 48 hrs by SRB assay
Phototoxicity against human T24 cells assessed as reduction in cell growth preincubated with compound for 24 hrs under dark condition and measured after 48 hrs by SRB assay
[PMID: 37708055]
T-24 EC50
> 25 μM
Compound: 5
Phototoxicity against human T24 cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by blue light irradiation at 468 nm for 7 mins 30 sec and measured after 48 hrs by SRB assay
Phototoxicity against human T24 cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by blue light irradiation at 468 nm for 7 mins 30 sec and measured after 48 hrs by SRB assay
[PMID: 37708055]
Molecular Weight

316.26

Formula

C16H12O7

CAS No.
SMILES

O=C1C2=CC(C)=CC(O)=C2C(C3=C(C(O)=C(C(O)=C13)OC)O)=O

Structure Classification
Initial Source

Dermocybe sanguinea

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Dermocybin
Cat. No.:
HY-N15601
Quantity:
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