2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. CYP11B2-IN-3

CYP11B2-IN-3 (compound 32) is an orally active and selective CYP11B2 inhibitor with IC50 values of 12.92 nM and 2341 nM for CYP11B2 and CYP11B1, respectively. CYP11B2-IN-3 can be used for study of hypertension.

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CYP11B2-IN-3 Chemical Structure

CYP11B2-IN-3 Chemical Structure

CAS No. : 3072732-90-9

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CYP11B2-IN-3 Related Antibodies

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View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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Description

CYP11B2-IN-3 (compound 32) is an orally active and selective CYP11B2 inhibitor with IC50 values of 12.92 nM and 2341 nM for CYP11B2 and CYP11B1, respectively. CYP11B2-IN-3 can be used for study of hypertension[1].

IC50 & Target

CYP11B2

12.92 nM (IC50)

Molecular Weight

394.90

Formula

C22H23ClN4O
CAS No.
SMILES

O=C(CC)N[C@H](CCC1)C2=C1C(C3=CC(Cl)=C(C4=CC=NN4C)C=C3)=CN=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CYP11B2-IN-3 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CYP11B2-IN-33072732-90-9Cytochrome P450CYPshypertensionInhibitorinhibitorinhibit

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